Proinflammatory Mediators Stimulate Neutrophil-Directed Angiogenesis
نویسندگان
چکیده
منابع مشابه
Proinflammatory mediators stimulate neutrophil-directed angiogenesis.
BACKGROUND Vascular endothelial growth factor (VEGF; vascular permeability factor) is one of the most potent proangiogenic cytokines, and it plays a central role in mediating the process of angiogenesis or new blood vessel formation. Neutrophils (PMNs) recently have been shown to produce VEGF. HYPOTHESIS The acute inflammatory response is a potent stimulus for PMN-directed angiogenesis. MET...
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BACKGROUND Lower airway secretions from patients with bronchiectasis show inflammatory cell infiltration and increased proinflammatory mediators. The aim of this study was to investigate the effects of antibiotic treatment for exacerbations on neutrophil apoptosis and necrosis. METHODS Sputum was induced from 15 subjects with idiopathic bronchiectasis at the beginning of an acute exacerbation...
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Background: Lower airway secretions from patients with bronchiectasis show inflammatory cell infiltration and increased proinflammatory mediators. The aim of this study was to investigate the effects of antibiotic treatment for exacerbations on neutrophil apoptosis and necrosis. Methods: Sputum was induced from 15 subjects with idiopathic bronchiectasis at the beginning of an acute exacerbation...
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Chemokines were originally described as cytokines that mediate leukocyte recruitment to sites of inflammation. Members of a subgroup of chemokines, the CXC family, also play a critical role in both physiologic and pathologic angiogenesis, including in the context of chronic inflammation, fibrosis, and malignancy. A unique feature of this family of cytokines is that, on the basis of their struct...
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ژورنال
عنوان ژورنال: Archives of Surgery
سال: 1999
ISSN: 0004-0010
DOI: 10.1001/archsurg.134.12.1325